MCQ Practice

The genome-wide comparative mRNA expression profile between normal and cancer cells can be studied using the microarray technology. The basic approach of this technology is

A

Hybridization of fluorescently labelled genomic DNA from human cells to normal and cancer cell cDNA immobilized onto two glass slides

B

Hybridization of fluorescently labelled cDNAs from normaland cancer cells to a single glass slide containing immobilized clones of human genomic DNA

C

Hybridization of fluorescently labelled cDNAs from normal and cancer cells to a single glass slide containing immobilized clones of human cDNAs

D

Hybridization of fluorescently labelled genomic DNA from normal and cancer cells to immobilized human cDNAs on a single glass slide

Correct Answer: C